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產(chǎn)品詳情
| 名稱： | anti- Histone-H3 antibody |
|---|---|
| 貨號： | FNab03890 |
| 適應(yīng)種屬： | 人源,大鼠,小鼠 |
| 規(guī)格： | 100ug(微克) |
| 狀態(tài)： | 液體 |
| 純化方法： | 免疫親和純化 |
| 純度： | 經(jīng)SDS-PAGE分析,純度大于95% |
| 宿主： | 兔 |
| 亞型： | lgG |
| 存儲： | 用添加了0.02%疊氮化鈉和50%甘油的PBS溶解,PH值7.3,可在-20℃下保存12個月（避免反復(fù)凍融） |
| 免疫原： | histone cluster 2, H3a |
| 免疫原別稱： | H3/n antibody, H3/o antibody, H3F2 antibody, H3FM antibody, HIST2H3A antibody, HIST2H3C antibody, HIST2H3D antibody, histone cluster 2 antibody, H3a antibody, Histone H3 antibody, Histone H3.2 antibody, Histone H3/m antibody, Histone H3/o antibo |
| 分子量： | 15-17 kDa |
| 驗(yàn)證應(yīng)用： | ELISA, WB, IHC, IF |
| 建議稀釋比例： | WB: 1:500-1:5000; IHC: 1:50-1:200; IF: 1:20-1:200 |
| UniProt ID： | Q71DI3 |
| 克隆性： | 多克隆 |
| 背景介紹： | HIST2H3A,histone cluster 2, H3a.It is the core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. HIST2H3A is Expressed during S phase, then expression strongly decreases as cell division slows down during the process of differentiation. |
| 圖像： |  Immunofluorescent analysis of HEK-293 cells using FNab03890 (Histone-H3 Antibody) at dilution of 1:50 and Rhodamine-Goat anti-Rabbit IgG。  Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab03890(Histone-H3 Antibody) at dilution of 1:50。  MCF7 cells were subjected to SDS PAGE followed by western blot with FNab03890(Histone-H3 antibody) at dilution of 1:1000。 |
